id author title date pages extension mime words sentences flesch summary cache txt cord-325657-s2vdazq0 Huang, Yan-Jang S. SARS-CoV-2 failure to infect or replicate in mosquitoes: an extreme challenge 2020-07-17 .txt text/plain 1589 105 46 Three widely distributed species of mosquito; Aedes aegypti, Ae. albopictus and Culex quinquefasciatus, representing the two most significant genera of arbovirus vectors that infect people, were tested. In this study, the susceptibility of three mosquito species, Ae. aegypti, Ae. albopictus and Cx. quinquefasciatus, were determined through the intrathoracic inoculation with SARS-CoV-2. No virus was detected in the 277 inoculated mosquitoes collected and titrated at time points beyond 24 h, suggesting a rapid loss of infectivity and the lack of replication after injection. Based upon the lack of detectable infectious virus in any of the 277 samples collected at all time points beyond 24 h post-inoculation, we conclude that SARS-CoV-2 is unable to replicate in mosquitoes and that even if a mosquito fed on a person with virus in the blood, that the mosquito would not be a vector if feeding on a naïve host. ./cache/cord-325657-s2vdazq0.txt ./txt/cord-325657-s2vdazq0.txt