id author title date pages extension mime words sentences flesch summary cache txt cord-325593-ww2vq3n4 Hendren, Nicholas S. Unique Patterns of Cardiovascular Involvement in COVID-19 2020-05-14 .txt text/plain 1298 71 35 However, to our knowledge, a framework describing the variable presentations of cardiac involvement in COVID-19 within the broader spectrum of symptomatic SARS-CoV-2 infection has not been previously proposed. First, the prevalence of mixed cardiopulmonary disease as assessed by elevated cardiac troponin levels, is variable, but occurs in 10-25% of patients hospitalized with COVID-19 3, 4 . ACovCS with cardiac predominate disease may be more apparent at hospital presentation relative to mixed cardiopulmonary disease because the predominate cardiac manifestations (e.g. chest pain due to a myocardial infarction) often results in symptoms which lead patients to seek emergent care. Just as there is variability in cardiac presentations of COVID-19, SARS-CoV-2 infection overall has a wide spectrum of disease penetrance with many patients displaying few to no symptoms, while an unfortunate minority develop severe life limiting disease. Other factors which may influence the variable presentation of COVID-19 include mutations in the circulating SARS-CoV-2 virus though it remains uncertain whether such observations explain the regional differences in the outcomes of COVID-19. ./cache/cord-325593-ww2vq3n4.txt ./txt/cord-325593-ww2vq3n4.txt