id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324623-x6eom6kh	Zhang, Jingyi	Effectiveness of Intravenous Immunoglobulin for Children with Severe COVID-19: A Rapid Review	2020-04-22		.txt	text/plain	4246	286	56	This rapid review aims to explore the clinical effectiveness and safety of IVIG in the treatment of children with severe COVID-19. Methods: We systematically searched the literature on the use of IVIG in patients with COVID-19, Severe Acute Respiratory Syndrome (SARS) or Middle East Respiratory Syndrome (MERS), including both adults and children. Results: A total of 1519 articles were identified by initial literature search, and finally six studies, included one randomized controlled trial (RCT), four case series and one case report involving 198 patients. The risk of death was not associated with the use of IVIG in the patients with ARDS (31) .A case report of three adults with COVID-19 reported that a high dose IVIG (25 g/d for 5 days) administered at the appropriate point could successfully block the progression of disease cascade (result of the clinical symptoms, laboratory inspection indicators and chest CT scan), and finally improve the outcome of COVID 19 (32) .	./cache/cord-324623-x6eom6kh.txt	./txt/cord-324623-x6eom6kh.txt