id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324619-y7gilopu	Alam, S.B.	Severe acute respiratory syndrome coronavirus‐2 may be an underappreciated pathogen of the central nervous system	2020-07-15		.txt	text/plain	5244	254	42	In this review, we examine some of the most recent data of COVID-19-associated neurological disease and the possibility that SARS-CoV-2 may be infecting the CNS. suggested that since SARS-CoV-2 shared significant similarities to severe acute respiratory syndrome coronavirus (SARS-CoV), it was entirely possible that SARS-CoV-2 could similarly penetrate the brain and CNS of infected patients through synapses in the medullary cardiorespiratory center and thereby cause respiratory failure (5) . Similar to these neurotropic HCoVs, SARS-CoV-2 infection in the lungs of some COVID-19 patients may also lead to entry into the CNS and this could occur via two main pathways: i) infection of peripheral nerves and retrograde axonal transport; and/or ii) hematogenous spread and infection of the cells of the blood-brain barrier. In this review, we have extrapolated information from other neurotropic viruses to make some predictions and it is clear that SARS-CoV-2 has the potential to infect the CNS and cause long-term neurologic damage in COVID-19 patients.	./cache/cord-324619-y7gilopu.txt	./txt/cord-324619-y7gilopu.txt