id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324328-olnwynfu	Nakamichi, K.	Outcomes associated with SARS-CoV-2 viral clades in COVID-19	2020-09-25		.txt	text/plain	4633	305	49	This study sought to determine whether SARS-CoV-2 sequence variants are associated with differing outcomes among COVID-19 patients in a single medical system. Statistical and machine learning models were applied to determine if viral genetic variants were associated with specific outcomes of hospitalization or death. Among patients sufficiently ill to warrant testing for virus, no significant difference in outcomes of hospitalization or death could be discerned between clades in this sample. Even though we found several baseline clinical factors to be significantly associated with clade 2 in univariate analyses and history of malignancy in the multivariate model, rates of hospitalization were not significantly different between patients infected with the two major clades of virus in our study (p=0.063), nor were mortality rates (p=0.58). Patient demographics and clinical history were strongly predictive of hospitalization, and viral clade information did not substantially improve predictions, suggesting that it contributes minimally to determination of outcome.	./cache/cord-324328-olnwynfu.txt	./txt/cord-324328-olnwynfu.txt