id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324255-ize21we2	Fouchier, Ron A. M.	Koch's postulates fulfilled for SARS virus	2003		.txt	text/plain	769	44	47	Severe acute respiratory syndrome (SARS) has recently emerged as a new human disease, resulting globally in 435 deaths from 6,234 probable cases (as of 3 May 2003). S evere acute respiratory syndrome (SARS) has recently emerged as a new human disease, resulting globally in 435 deaths from 6,234 probable cases (as of 3 May 2003) . We inoculated two macaques with Vero-cellcultured SCV isolated from a fatal SARS case, and monitored their clinical signs, virus excretion and antibody response. The macaques excreted virus from the nose and throat at 2-6 d.p.i., as shown by polymerase chain reaction with reverse transcription (RT-PCR) and by virus isolation (see supplementary information). At gross necropsy, one macaque had severe multifocal pulmonary consolidation, and SCV infection was detected in lung tissue by RT-PCR and virus isolation. However, these were not present in SCV-inoculated macaques (results not shown), were not found consistently in SARS patients, and do not usually cause the lesions associated with SARS.	./cache/cord-324255-ize21we2.txt	./txt/cord-324255-ize21we2.txt