id author title date pages extension mime words sentences flesch summary cache txt cord-324128-css42bsb Boukli, Narjis High Incidence of False-Positive Results in Patients with Acute Infections Other than COVID-19 by the Liaison SARS-CoV-2 Commercial Chemiluminescent Microparticle Immunoassay for Detection of IgG Anti-SARS-CoV-2 Antibodies 2020-10-21 .txt text/plain 949 56 53 title: High Incidence of False-Positive Results in Patients with Acute Infections Other than COVID-19 by the Liaison SARS-CoV-2 Commercial Chemiluminescent Microparticle Immunoassay for Detection of IgG Anti-SARS-CoV-2 Antibodies The median day of IgG seroconversion is around 14 days after symptom onset (2), but a high interindividual variation has been reported, as well as contrasting performances between commercial assays (3) (4) (5) (6) . Furthermore, the 100 samples in our specificity panel were negative with the Alinity I SARS-CoV-2 IgG assay, except for one serum sample from a patient with coronavirus 229E infection, which was weakly reactive (signal-to-cutoff index ϭ 1.93; cutoff is 1.4 index), which leads to a specificity of 99%. While the clinical significance of SARS-Cov-2 antibody detection remains to be determined, our results confirm that careful evaluation of the tests on appropriate samples is required before implementing assays for routine use. ./cache/cord-324128-css42bsb.txt ./txt/cord-324128-css42bsb.txt