id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-323394-osx7llte	Lanser, Lukas	Evaluating the clinical utility and sensitivity of SARS-CoV-2 antigen testing in relation to RT-PCR Ct values	2020-11-13		.txt	text/plain	1214	63	53	We compared the SARS-CoV-2 antigen detection in nasopharyngeal swab samples by the Panbio™ COVID-19 Ag Rapid test (Abbott, Chicago, Illionis) with the simultaneous routinely conducted RT-PCR analysis of SARS-CoV-2 orf1 RNA detection with the cobas ® analyzer (Roche Diagnostics GmbH, Mannheim, Germany). Among 51 RT-PCR SARS-CoV-2 positive patients, the Pan-bio™ COVID-19 Ag Rapid test was positive in 31 subjects depicting a poor sensitivity of 60.8% (95% CI 46.1-74.2%), compared to 93.3% in the manufacturer's information. In the 14 patients with a Ct-value ≤ 25, being indicative for higher viral loads, the sensitivity for the Panbio™ COVID-19 Ag Rapid test was at a level of 85.7% (95% CI 57.2-98.2%, Table 1 ). Although our results are quite encouraging regarding the use of antigen test as point-of-care diagnostic which may contribute to a better control of the pandemic, we need longitudinal studied which larger patient cohorts to corroborate our results and to develop algorithms or to identify those subjects who are contagious but not detected by that test.	./cache/cord-323394-osx7llte.txt	./txt/cord-323394-osx7llte.txt