id author title date pages extension mime words sentences flesch summary cache txt cord-322473-fmob6k0q Charpiat, Bruno Proton Pump Inhibitors are Risk Factors for Viral Infections: Even for COVID-19? 2020-08-10 .txt text/plain 1573 76 42 During the ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), more attention should be paid to the balance of risks and benefits associated with proton pump inhibitors for the following reasons. Studies have documented that proton pump inhibitors are a risk factor for rotavirus, influenza virus, norovirus, and Middle East respiratory syndrome coronavirus infections, and are associated with an increased risk of acute gastroenteritis during periods of highest circulation of enteric viruses. Given the magnitude of the SARS-CoV-2/COVID-19 pandemic, associated with the widespread misuse of PPIs, this suggests that we cannot/should not rule out the hypothesis that patients treated with PPIs may be more at risk of being infected by COVID-19. They, therefore, hypothesized that PPI treatment may also be a potential risk factor for the development of secondary infections and of acute respiratory distress syndrome in hospitalized patients with COVID-19 [12] . ./cache/cord-322473-fmob6k0q.txt ./txt/cord-322473-fmob6k0q.txt