id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-322044-4eejzpmn	Frediansyah, Andri	Remdesivir and its antiviral activity against COVID-19: A systematic review	2020-08-07		.txt	text/plain	613	55	47	title: Remdesivir and its antiviral activity against COVID-19: A systematic review BACKGROUND: To summarize the antiviral activities of remdesivir against SARS-CoV-2, the causative agent of COVID-19. Although remdesivir has been used as a compassionate drug for treating COVID-19 patients, it has only moderate efficacy. CONCLUSION: Although remdesivir has shown potent antiviral activities, more efficacy assessments are urgently warranted in clinical trials. The first randomized, double-blind, placebo-controlled, multicenter clinical trial was 175 reported on April 29, 2020 [48] . Prophylactic 341 and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of 342 MERS-CoV infection Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2 Compassionate use 355 of remdesivir for patients with severe Covid-19 The authors whose names are listed immediately below report the following details of affiliation or involvement in an organization or entity with a financial or non-financial interest in the subject matter or materials discussed in this manuscript.	./cache/cord-322044-4eejzpmn.txt	./txt/cord-322044-4eejzpmn.txt