id author title date pages extension mime words sentences flesch summary cache txt cord-321468-nkl2mls8 Yang, Mo Thrombopoietin levels increased in patients with severe acute respiratory syndrome 2008-03-07 .txt text/plain 2433 118 53 Using a ELISA method, we found an increase in thrombopoietin (TPO) levels in the plasma of convalesced SARS patients (290 ± 53 pg/ml) and active SARS patients (251 ± 23 pg/ml) comparing to that from normal control patients (228 ± 17 pg/ml). Severe Acute Respiratory Syndrome (SARS) is a recently emerged human disease caused by the infection of a novel coronavirus (SARS-CoV) [1] . In this study, TPO levels in plasmas from SARS patients, the effect of these plasmas on in vitro megakaryocytopoiesis, and whether SARS-CoV can directly infect hematopoietic stem cells and megakaryocytic cells are investigated. To study the correlation of platelet counts and the plasma TPO levels, linear regression analyses were carried out for the normal, convalesced SARS and active SARS patient groups respectively. The present study showed that there was an increase of TPO levels in the plasma of convalescence SARS patients comparing to those from normal control and active SARS patients. ./cache/cord-321468-nkl2mls8.txt ./txt/cord-321468-nkl2mls8.txt