id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-320673-4guarm0k	Lopera, E.	Lack of association between genetic variants at ACE2 and TMPRSS2 genes involved in SARS-CoV-2 infection and human quantitative phenotypes	2020-04-25		.txt	text/plain	4180	215	47	title: Lack of association between genetic variants at ACE2 and TMPRSS2 genes involved in SARS-CoV-2 infection and human quantitative phenotypes While large-scale genetic studies of COVID-19 patients are being assembled, such as those coordinated by the COVID host genetics consortium (https://www.covid19hg.com/), it is worthwhile to evaluate the effects of genetic variants in genes involved in SARS-CoV-2 infection on human phenotypes, including quantitative traits, taking advantage of already existing cohorts. Therefore, understanding the role of genetic variants at genes essential for SARS-CoV-2 infection in human quantitative phenotypes is important to explain the observed variability in infection susceptibility and severity of COVID-19 and this understanding may suggest potential treatments. In conclusion we carried out an extensive screening of potential genetic associations at common and low frequency variants in the ACE2 and TMPRSS2 genes, and found a lack of substantial effect in human quantitative phenotype variation in the general population.	./cache/cord-320673-4guarm0k.txt	./txt/cord-320673-4guarm0k.txt