id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-320511-qnxj7d9l	Hueston, Linda	The antibody response to SARS-CoV-2 infection	2020-08-27		.txt	text/plain	3106	180	47	METHODS: A SARS-CoV-2-specific immunofluorescent antibody (IFA) assay for IgG, IgA and IgM was developed, and prospectively evaluated by comparison to the reference standard of NAT on respiratory tract samples from individuals with suspected COVID-19. Diagnosis is primarily by detecting SARS-CoV-2-specific RNA by nucleic acid testing (NAT), but this has limitations, including the possibility of false-negative results due to low virus load in patients with minimal disease, inadequate respiratory tract sampling or mutations in the target sequence, and false-positive results due to contamination or nonspecific amplification. The objective of this study was to develop and evaluate an immunofluorescent antibody (IFA) test for SARS-CoV-2-specific IgG, IgM and IgA, and apply it to document the serological response in individuals with confirmed COVID-19. Since the start of the epidemic in Australia, the Public Health Laboratory Network recommended collecting acute and convalescent sera for serological assays on individuals being tested for SARS-CoV-2 infection, in addition to respiratory tract samples for NAT, though this has not been universally adopted [5] .	./cache/cord-320511-qnxj7d9l.txt	./txt/cord-320511-qnxj7d9l.txt