id author title date pages extension mime words sentences flesch summary cache txt cord-319964-ju9japd8 Lu, Jing Genomic epidemiology of SARS-CoV-2 in Guangdong Province, China 2020-04-04 .txt text/plain 4100 250 53 Highlights: 1) 1.6 million molecular diagnostic tests identified 1,388 SARS-CoV-2 infections in Guangdong Province, China, by 19th March 2020; 2) Virus genomes can be recovered using a variety of sequencing approaches from a range of patient samples. In order to understand the molecular epidemiology and genetic diversity of SARS-CoV-2 in China we generated 53 genomes from infected individuals in Guangdong using a combination of metagenomic sequencing and tiling amplicon approaches. https://doi.org/10.1101/2020.04.01.20047076 doi: medRxiv preprint To understand the genetic diversity of the SARS-CoV-2 epidemic in Guangdong we performed phylogenetic analyses using maximum likelihood and Bayesian molecular clock approaches. https://doi.org/10.1101/2020.04.01.20047076 doi: medRxiv preprint Our analyses of the genomic epidemiology of SARS-CoV-2 in Guangdong province indicate that, following the first COVID-19 case detected in early January, most infections were the result of virus importation from elsewhere, and that chains of local transmission were limited in size and duration. ./cache/cord-319964-ju9japd8.txt ./txt/cord-319964-ju9japd8.txt