id author title date pages extension mime words sentences flesch summary cache txt cord-317928-doj39520 Thum, Thomas SARS-CoV-2 receptor ACE2 expression in the human heart: cause of a post-pandemic wave of heart failure? 2020-05-14 .txt text/plain 1462 85 48 A number of pre-clinical studies have shown various organ systems to express the primary SARS-CoV-2 entry receptor, angiotensin-converting enzyme 2 (ACE2). Potentially, the COVID-19 outbreak will also lead to an increase of long-term complications of patients with CVD such as heart failure in both patients infected with SARS-CoV-2 and those that are not infected but that were treated suboptimally during the ongoing pandemic ( Figure 1 ). In conclusion, Nicin and co-workers report here an important observation with future implications in both research and, potentially, treatment of SARS-CoV-2-infected cardiovascular patients. These novel data at least suggest that it will be important to monitor SARS-CoV-2-infected patients for cardiovascular complications and assess the impact of ARB/ACE inhibitor therapy in more detail. Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2 ./cache/cord-317928-doj39520.txt ./txt/cord-317928-doj39520.txt