id author title date pages extension mime words sentences flesch summary cache txt cord-317429-pp6hb4q5 Aslam, Saima COVID-19: Yet another coronavirus challenge in transplantation 2020-03-14 .txt text/plain 1405 78 47 A novel coronavirus, severe acute respiratory syndrome −coronavirus-2 (SARS-CoV-2), causing a severe acute respiratory syndrome with its disease designated as COVID-19, emerged from its epicenter in Wuhan, China, in December 2019 and is now a global pandemic. 7 report on the presentation and outcome of 2 microbiologically confirmed COVID-19 cases in heart transplantation detected in the Hubei Province in China. These 2 patients apparently were part of a community of at least 200 heart transplant survivors in that region and presented with variable severity of disease (one mild and another with more severe manifestations requiring a prolonged hospitalization); however, both survived the event. It is important to note that the clinical presentations were not distinct from those described in non-immunosuppressed individuals, and the patient with severe disease presented with a viral prodrome, displayed the typical findings on CT scan imaging, and progressed to clinical hypoxia. In summary, the novel coronavirus and its disease, COVID-19, require thoughtful approaches for the prevention, mitigation, timely detection, and appropriate therapeutic intervention for our vulnerable patients. ./cache/cord-317429-pp6hb4q5.txt ./txt/cord-317429-pp6hb4q5.txt