id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-317233-k3wuqwyu	Lorenzo-Redondo, Ramon	A clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways	2020-11-11		.txt	text/plain	8170	400	52	INTERPRETATION: These results show that multiple variants of SARS-CoV-2 were circulating in the Chicago area in mid-March 2020 that differed in their relative viral loads in patient upper airways. While the predominant virus genotype in Washington state was most closely related to viruses in China in the early epidemic, the predominant virus genotype in New York was more closely related to viruses from Europe [12] .The latter viruses carry a mutation in their Spike protein (D614G) that has not only become more common worldwide over time, but that has also been associated with higher viral loads in COVID-19 patients. Furthermore, this study supports a correlation between SARS-CoV-2 clade and relative viral load in the upper airways of infected patients. In this study, we report the phylogenetic and phylodynamic analyses of 88 SARS-CoV-2 genomes from COVID-19 patients in Chicago, Illinois, US, which largely fall into three major clades.	./cache/cord-317233-k3wuqwyu.txt	./txt/cord-317233-k3wuqwyu.txt