id author title date pages extension mime words sentences flesch summary cache txt cord-317067-u90zkjk9 Trottein, François Potential causes and consequences of gastrointestinal disorders during a SARS-CoV-2 infection 2020-07-03 .txt text/plain 639 48 44 Intensive research on the pathogenic mechanisms used by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is urgently needed – notably in order to identify potential drug targets. Here, we review gastrointestinal disorders in patients with COVID-19, suggest hypothetical mechanisms leading to gut symptoms, and discuss the potential consequences of gastrointestinal disorders on the outcome of the disease. Lastly, we discuss the role of the gut microbiota during respiratory viral infections and suggest that targeting gut dysbiosis may help to control the pathogenesis of COVID-19. In this review, Trottein & Sokol present hypothetical mechanisms leading to gut symptoms in patients with COVID-19 and discuss their potential consequences on disease severity. They also discuss the role of the gut microbiota in disease and the potential interest of targeting it to improve COVID-19 pathogenesis. Clinical characteristics of 138 hospitalized patients with 2019 novel 589 coronavirus-infected pneumonia in Wuhan, China ./cache/cord-317067-u90zkjk9.txt ./txt/cord-317067-u90zkjk9.txt