id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-316946-bxfdq8e1	Danion, François	The Good, the Bad, and the Hoax: When Publication Instantaneously Impacts Treatment Strategies for COVID-19	2020-07-22		.txt	text/plain	762	50	49	In Strasbourg University Hospital, France, which was severely affected by the SARS-CoV-2 epidemic at the beginning of March 2020, we analyzed the consumption of antiviral agents according to the emergence of relevant scientific data. The treatment strategies in our center, outside clinical trials, included standard of care alone or in combination with lopinavir-ritonavir or hydroxychloroquine (HCQ) in off-label utilization and without grading of the recommendations. Despite the major limitations of this study-including no outcome data on clinical efficacy or safety, the small number of patients enrolled, and the absence of randomization-we experienced a dramatic increase in our HCQ prescriptions following this publication (Fig. 1) . Following the publication of a large observational study on 22 May showing no beneficial effect of HCQ, this treatment regimen is not authorized anymore in France outside clinical trials (6) . Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial	./cache/cord-316946-bxfdq8e1.txt	./txt/cord-316946-bxfdq8e1.txt