id author title date pages extension mime words sentences flesch summary cache txt cord-316930-0s7k9guq Caldas, Lucio Ayres Ultrastructural analysis of SARS-CoV-2 interactions with the host cell via high resolution scanning electron microscopy 2020-09-30 .txt text/plain 2901 192 52 title: Ultrastructural analysis of SARS-CoV-2 interactions with the host cell via high resolution scanning electron microscopy Intercellular connections were also approached, and viral particles were adhered to these extensions suggesting direct cell-to-cell transmission of SARS-CoV-2. At the same time, and with a MOI of 1, viruses that egressed from a previous cycle of infection were observed during the process of attachment to the cell plasma membrane ( Fig. 2A) . To approach SARS-CoV-2/cell interactions, we investigate several steps of virus infection in Vero cells at 2 and 48 hpi by SEM. These sites were appropriate to register the attachment of SARS-CoV-2 particles ( Fig. 2A ) similar to transmission electron microscopy images of the same early step of SARS-CoV infection of Vero cells 28 . Drastic vacuolization due to viral infection was previously described for other RNA viruses including SARS-CoV 20,32 . ./cache/cord-316930-0s7k9guq.txt ./txt/cord-316930-0s7k9guq.txt