id author title date pages extension mime words sentences flesch summary cache txt cord-316667-b1xabkzk Konopka, Kristine E. Diffuse Alveolar Damage (DAD) from Coronavirus Disease 2019 Infection is Morphologically Indistinguishable from Other Causes of DAD 2020-06-15 .txt text/plain 2694 157 45 Additionally, to better understand if COVID-19 represents a histologic variant of DAD we systematically compare the pathologic findings of SARS-CoV-2-positive patients to uninfected controls. 11 Our autopsy databases were then searched from January 1, 2016 through December 31, 2019 for inpatient and nonhospitalized community cases diagnosed as "diffuse alveolar damage." Since these deaths occurred prior to the first reported case of COVID-19 in the United States, 12 they are considered SARS-CoV-2negative (further referred to as "control cohort"). To our knowledge, this is the first comparison of autopsy lung findings in SARS-CoV-2-positive medically managed inpatients and untreated, non-hospitalized decedents to uninfected historical control cases of DAD. Nonetheless, we think our SARS-CoV-2 positive cases are likely representative of the broader COVID-19 patient population, since both hospitalized and non-hospitalized decedents had underlying conditions previously identified as risk factors for severe disease, including diabetes, chronic lung disease, cardiovascular disease, 13 and obesity. ./cache/cord-316667-b1xabkzk.txt ./txt/cord-316667-b1xabkzk.txt