id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-316646-rd3zl9qz	Lebedin, Y. S.	Serum SARS-CoV-2 nucleocapsid antigen detection is essential for primary diagnostics of SARS-CoV-2-associated pneumonia	2020-09-25		.txt	text/plain	2531	132	49	The article highlights the diagnostic value of SARS-CoV-2 seroconversion in patients with pneumonia based on the results of a retrospective study conducted at the height of the COVID-19 pandemic in Moscow, Russia In this report, we evaluate the SARS-CoV-2 nucleocapsid antigen (N-Ag) and respective antibodies as diagnostic markers and demonstrate the total prevalence of N-Ag seroconversion in SARS-CoV-2-associated pneumonia patients. The immunoassay-based detection of serum N-Ag in combination with its respective antibodies confirmed COVID-19 in 280 patients (59%) of the studied cohort. The results indicate high relevance of combined serological tests for SARS-CoV-2 N-Ag and the antibodies to SARS-CoV-2 antigens as applied to the infectious pneumonia emergency patients at the admission, since: According to the results of the study, hospitalization of the patients with SARS-CoV-2associated pneumonia at the height of pandemic most frequently occurred before the onset of seroconversion (i.e. against the background of detectable serum N-Ag concentrations).	./cache/cord-316646-rd3zl9qz.txt	./txt/cord-316646-rd3zl9qz.txt