id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-316180-g3lfecp0	Zhang, Jingshu	Membrane heist: Coronavirus host membrane remodeling during replication	2020-10-25		.txt	text/plain	1790	122	43	Here we review the current knowledge of the structure, lipid composition, function, and biogenesis of coronavirus-induced DMVs, highlighting the druggable viral and cellular factors that are involved in the formation and function of DMVs. Prior to the emergence of Coronavirus Disease-2019 (COVID-19) caused by severe 2 acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the outbreak of highly approximately 50 to 250 nm of these DMVs as described in detail elsewhere 9, 10 . Severe 503 acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 504 induce double-membrane vesicles Mutation in 521 murine coronavirus replication protein nsp4 alters assembly of double 522 membrane vesicles Expression and cleavage of middle east respiratory 537 syndrome coronavirus nsp3-4 polyprotein induce the formation of double-538 membrane vesicles that mimic those associated with coronaviral RNA 539 replication The N-terminal region of severe acute respiratory syndrome 546 coronavirus protein 6 induces membrane rearrangement and enhances virus 547 replication	./cache/cord-316180-g3lfecp0.txt	./txt/cord-316180-g3lfecp0.txt