id author title date pages extension mime words sentences flesch summary cache txt cord-315968-q2rxj90s Douglas, Jennifer E. Management of a Unique Sinonasal Undifferentiated Carcinoma Subtype in the Era of SARS-CoV-2 2020-10-05 .txt text/plain 1379 80 43 Sinonasal undifferentiated carcinoma (SNUC) represents a rare malignancy of the sinonasal tract, a unique subset of which has never been previously reported in the otolaryngology literature and is characterized by inactivation of the SMARCB (INI-1) tumor suppressor gene. Here we present the case of an individual who was diagnosed with a sinonasal mass during the SARS-CoV-2 pandemic, which was ultimately found to be SMARCB (INI-1)-deficient sinonasal carcinoma. While SNUC has itself a poor prognosis, a subset of sinonasal neoplasms with inactivation of the SMARCB (INI-1) tumor suppressor gene exhibits particularly treatment-recalcitrant disease. Here we present the case of an individual with a sinonasal mass who was ultimately diagnosed with SMARCB (INI-1)-deficient sinonasal carcinoma and the unique management required during the SARS-CoV-2 pandemic. Here we present the case of an individual initially diagnosed with nasal polyps who was ultimately diagnosed with SMARCB (INI-1)-deficient sinonasal carcinoma during the SARS-CoV-2 pandemic and the unique management required. ./cache/cord-315968-q2rxj90s.txt ./txt/cord-315968-q2rxj90s.txt