id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-315604-a6fvsd45	Maurya, Santosh K.	Virtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/NSP16 methyltransferase and main protease of SARS CoV-2	2020-06-01		.txt	text/plain	3219	198	55	title: Virtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/NSP16 methyltransferase and main protease of SARS CoV-2 We found that top screened compound binds with protein molecules with good dock score with the help of hydrophobic interactions and hydrogen bonding. HIGHLIGHTS: NSP10/NSP16 methyltransferase and main protease complex of SARS CoV-2 bind with selected drugs. Hydrophobic interaction successfully delineates specific functional groups that may be responsible for the hydrophobic generating effect of these compounds with strong binding affinity against target proteins and may play a highly influencing against SARS-CoV-2 infection All the compounds showed good binding free energy with their respective proteins of SARS-CoV-2. In this study, it has been shown that selected screened compounds have good docking score, high DG binding free energy as well as strong hydrophobic interactions, and follows the Lipinski rule of five.	./cache/cord-315604-a6fvsd45.txt	./txt/cord-315604-a6fvsd45.txt