id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-315337-vgi91uzg	Mizutani, Tetsuya	Characterization of Persistent SARS-CoV Infection in Vero E6 Cells	2006		.txt	text/plain	912	63	54	A human intestinal cell line, LoVo, was shown to permit SARS-CoV infection, resulting in the establishment of persistent infection. This cell line expresses the viral receptor ACE-2 4 at high levels, and SARS-CoV infection of Vero E6 causes cytopathic effects within 24 h. In the present study, we established a persistently SARS-CoV-infected cell line after passage 6. Here, we reported a possible mechanism of the establishment of persistent SARS-CoV infection in Vero E6 cells (Fig. 2) . Although the majority of cells died due to apoptosis after SARS-CoV infection, activation of JNK and PI3K/Akt signaling pathways aided a minor population of cells with the potential to support persistent infection to establish persistence. pathways are required for establishing persistent SARS-CoV-infection in Vero E6 cells	./cache/cord-315337-vgi91uzg.txt	./txt/cord-315337-vgi91uzg.txt