id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-313305-tih33rys	Castro, Rodolfo	COVID-19: a meta-analysis of diagnostic test accuracy of commercial assays registered in Brazil	2020-04-18		.txt	text/plain	838	55	54	We searched at the Brazilian Health Regulatory Agency (ANVISA) online platform to describe the pooled sensitivity (Se), specificity (Sp), diagnostic odds ratio (DOR) and summary receiver operating characteristic curves (SROC) for detection of IgM/IgG antibodies and for tests using naso/oropharyngeal swabs in the random-effects models. Pooled diagnostic accuracy measures [95%CI] were: (i) for IgM antibodies Se=82% [76-87]; Sp=97% [96-98]; DOR=168 [92-305] and SROC=0.98 [0.96-0.99]; (ii) for IgG antibodies Se=97% [90-99]; Sp=98% [97-99]; DOR=1994 [385-10334] and SROC=0.99 [0.98-1.00]; and (iii) for detection of SARS-CoV-2 by antigen or molecular assays in naso/oropharyngeal swabs Se=97% [85-99]; Sp=99% [77-100]; DOR=2649 [30-233056] and SROC=0.99 [0.98-1.00]. The aim of this study was to perform a meta-analysis to describe the accuracy of available tests to detect COVID-19 in Brazil. Our study reports that antigen testing and/or molecular assays using nasopharyngeal and oropharyngeal specimens had high accuracy for SARS-CoV-2 detection.	./cache/cord-313305-tih33rys.txt	./txt/cord-313305-tih33rys.txt