id author title date pages extension mime words sentences flesch summary cache txt cord-313076-531wksez Rauch, J. N. CRISPR-based and RT-qPCR surveillance of SARS-CoV-2 in asymptomatic individuals uncovers a shift in viral prevalence among a university population 2020-08-07 .txt text/plain 5576 313 54 Our results substantiate that large, population-level asymptomatic screening using self-collection may be a feasible and instructive aspect of the public health approach within large campus communities, and the almost perfect concordance between CRISPRand PCR-based assays indicate expanded options for surveillance testing The objectives of our study were to: (i) establish the prevalence of asymptomatic SARS-CoV2 infection in a university population, (ii) assess for any dynamic change associated with the changing community conditions related to NPIs, and (iii) systematically compare the performance of our newly developed CRISPR-based test alongside that of the established, CDC-recommended reference testing by RT-qPCR. We used two assays to detect SARS-CoV-2 genomes in the collected OP swab samples: a CRISPR-based method we recently developed at UCSB known as CREST 23 , and the RT-qPCR test recommended by the CDC 24 (Sup. Fig. ./cache/cord-313076-531wksez.txt ./txt/cord-313076-531wksez.txt