id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-312984-rzryn3on	Pan, Daniel	Serial simultaneously self-swabbed samples from multiple sites show similarly decreasing SARS-CoV-2 loads in COVID-19 cases of differing clinical severity	2020-09-19		.txt	text/plain	946	63	59	title: Serial simultaneously self-swabbed samples from multiple sites show similarly decreasing SARS-CoV-2 loads in COVID-19 cases of differing clinical severity 8 From this small longitudinal cohort study on serially collected samples in acute COVID-19 cases of differing severity, we conclude that for symptomatic patients, it is difficult to obtain a 'false negative' result on NPS, OPS, NS or CS samples, if sampled early (within 5 days) post-symptom onset, even if the swab was 'poorly' taken. Despite a previous meta-analysis showing that sputum testing is possibly more sensitive for SARS-CoV-2 PCR testing, 9 other studies have shown that self-sampling from various URT sites performed satisfactorily for the diagnosis of acute COVID-19. Therefore, we further confirm that early (within 5 days of symptom onset), self-swabbed NPS, OPS, NS or CS samples for SARS-CoV-2 diagnostic testing in acute COVID-19 cases is a sensitive, practical approach, which reduces patient discomfort (as self-swabbing can be controlled) and minimises virus exposure to healthcare workers.	./cache/cord-312984-rzryn3on.txt	./txt/cord-312984-rzryn3on.txt