id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-312115-foy3dsq4	Sekine, Takuya	Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19	2020-08-14		.txt	text/plain	4891	272	52	In line with these data, we found that CD8 + T cells specific for cytomegalovirus (CMV) or Epstein-Barr virus (EBV) more commonly expressed CD38, but not HLA-DR, Ki-67, or PD-1, in patients with acute moderate or severe COVID-19 compared with convalescent individuals and healthy blood donors, indicating limited bystander activation and proliferation during the early phase of infection with SARS-CoV-2 ( Figure 2A , B and Figure S3C ). On the basis of these observations, we quantified functional SARS-CoV-2-specific memory T cell responses across five distinct cohorts, including healthy individuals who donated blood either before or during the pandemic, family members who shared a household with convalescent individuals and were exposed at the time of symptomatic disease, and individuals in the convalescent phase after mild or severe COVID-19. These donors exhibited robust memory T cell responses months after infection, even in the absence of detectable circulating antibodies specific for SARS-CoV-2, indicating a previously unanticipated degree of population-level immunity against COVID-19.	./cache/cord-312115-foy3dsq4.txt	./txt/cord-312115-foy3dsq4.txt