id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-310184-qth1y88o	Alunno, Alessia	Storm, typhoon, cyclone or hurricane in patients with COVID-19? Beware of the same storm that has a different origin	2020-05-18		.txt	text/plain	2981	143	38	Some of the articles being published during the severe acute respiratory syndrome–coronavirus (SARS-CoV)-2 pandemic highlight a link between severe forms of coronavirus disease 2019 (COVID-19) and the so-called cytokine storm, also with increased ferritin levels. Some patients with coronavirus 2019 disease (COVID-19) develop a fully blown secondary haemophagocytic lymphohistiocytosis (sHLH), whereas others, despite a consistent release of pro-inflammatory cytokines, do not fulfil sHLH criteria but still show some features resembling the phenotype of the hyperferritinemic syndrome. Other immunomodulating agents like IL-1 or IL-6 inhibitors are only recommended in selected cases including the macrophage activation syndrome (MAS), a subtype of sHLH associated with systemic juvenile idiopathic arthritis (sJIA), adult-onset Still's disease (AOSD) and other autoimmune disorders.	./cache/cord-310184-qth1y88o.txt	./txt/cord-310184-qth1y88o.txt