id author title date pages extension mime words sentences flesch summary cache txt cord-310064-p8u424ch Katz, Andrew P. False‐positive reverse transcriptase polymerase chain reaction screening for SARS‐CoV‐2 in the setting of urgent head and neck surgery and otolaryngologic emergencies during the pandemic: Clinical implications 2020-06-12 .txt text/plain 4503 242 49 [4] [5] [6] The virus responsible for COVID-19, SARS-CoV-2, poses a particular risk to providers involved in the care of otolaryngology patients due to examinations and surgeries involving the nasopharynx, oropharynx, and upper aerodigestive tract, which harbor high concentrations of viral particles. 6 In line with other institutions across the globe, these protocols call for preoperative testing of asymptomatic patients using reverse transcriptase polymerase chain reaction (RT-PCR) given reports of asymptomatic carriers of SARS-CoV-2 capable of transmission. Tahamtan and Ardebili discuss possible factors causing false negative results of SARS-CoV-2 RT-PCR, namely mismatches between the testing primers and viral genome or low viral loads in samples due to timing of disease or location of collection. In the most recent patient with positive preoperative testing without symptoms (patient #3), pathologists recommended immediate re-testing based on the borderline titers in her test results rather than delaying surgery for weeks for a potential COVID-19 infection. ./cache/cord-310064-p8u424ch.txt ./txt/cord-310064-p8u424ch.txt