id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-310063-8nbmrjrw	Selva, K. J.	Distinct systems serology features in children, elderly and COVID patients	2020-05-18		.txt	text/plain	3779	218	55	. https://doi.org/10.1101 /2020 6 147 To interrogate Ab functionality and cross-reactivity between antigens of selected CoV signatures, we 148 conducted a correlation network analysis, focusing upon significant correlations of Ab features 149 selected by Elastic-Net. The children's network (Figure 1f ) demonstrates how SARS-CoV-2 Abs that 150 engaged FcγRIIa-H131 are associated with SARS-CoV-2 IgG, specifically of IgG1 subclass. In particular, we found that in the majority of COVID-19 190 patients, the SARS-CoV-2 antigen-specific Abs bound to FcγRIIIaV158 and FcγRIIaH131 soluble 191 dimers at high levels, even at 1:800 plasma titrations, suggesting potent ADCC and ADCP CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. . https://doi.org/10.1101/2020.05.11.20098459 doi: medRxiv preprint 8 notably being the healthy exposed SARS-CoV-2 PCR-negative individual (Figure 3d) The majority of COVID-19 moderate/severe samples were collected upon hospital presentation, 235 whereas mild samples were collected upon convalescence (Extended Data Table 3 ).	./cache/cord-310063-8nbmrjrw.txt	./txt/cord-310063-8nbmrjrw.txt