id author title date pages extension mime words sentences flesch summary cache txt cord-309856-flkjl1dm Westblade, Lars F. SARS-CoV-2 Viral Load Predicts Mortality in Patients with and Without Cancer Who Are Hospitalized with COVID-19 2020-09-15 .txt text/plain 1971 96 52 For data generated using the cobas assay, we used viral load cutoffs based on C T values for the 123 ORF1ab gene target that were previously shown to correlate with in-hospital mortality among 124 hospitalized patients with COVID-19: high, C T value <25; medium, C T value 25-30, low, C T value 125 >30 (Magleby et al., 2020) . In the overall cohort, using assay-specific C T value cutoffs, 38.8% of patients with a high viral 156 load died during their hospitalization, compared to 24.1% of patients with a medium viral load, active cancer that adjusted for age and need for supplemental oxygen within 3 hours of 169 presentation to the ED (Table 4) , we found that having a high viral load was independently 170 associated with increased in-hospital mortality (aOR 5.00; 95% CI: 1. In conclusion, using two different diagnostic platforms, we found that admission SARS-CoV-2 277 viral load, as assessed by C T values that are generated by routine RT-PCR diagnostic assays, 278 was highly associated with in-hospital mortality in COVID-19 patients with and without cancer. ./cache/cord-309856-flkjl1dm.txt ./txt/cord-309856-flkjl1dm.txt