id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-308996-tf0v2ojk	Maas, Angela HEM	The Coronavirus Disease 2019 Outbreak Highlights the Importance of Sex-sensitive Medicine	2020-08-24		.txt	text/plain	2188	138	45	The novel coronavirus disease 2019 (COVID-19) pandemic has revealed important differences between the sexes in epidemiology, risk factors, clinical course, mortality and socioeconomic dimensions of the disease in all populations worldwide. The role of the TMPRSS2 protease in SARS-CoV-2 needs to be further investigated, but information on other diseases points towards sexspecific differences. 34 Sex differences in the binding of SARS-CoV-2 to the ACE2 receptor have been identified as an important contributor to the initiation and course of the disease. 27, 35, 36 Sex differences regarding potential protective effects of renin-angiotensin-aldosterone system inhibitors in SARS-CoV-2 infections are as yet unknown. Sex-specific SARS-CoV-2 mortality: among hormone-modulated ACE2 expression, risk of venous thromboembolism and hypovitaminosis D The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2 Gender differences in patients with COVID-19: focus on severity and mortality	./cache/cord-308996-tf0v2ojk.txt	./txt/cord-308996-tf0v2ojk.txt