id author title date pages extension mime words sentences flesch summary cache txt cord-308831-u5bj1sod Chaung, Jenna Coinfection with COVID‐19 and Coronavirus HKU1 – the critical need for repeat testing if clinically indicated 2020-04-15 .txt text/plain 1008 70 54 COVID-19 is the latest global pandemic caused by the severe acute respiratory syndrome coronavirus -2 (SARS-CoV-2). We describe a case of endemic HCoV co-infection with SARS-CoV-2 in a patient with COVID-19. Nasopharyngeal swabs were sent on day 1 of admission, one was positive for HCoV-HKU1 on the FilmArray Respiratory Panel (RP) (BioFire Diagnostics, bioMerieux) but another was negative for SARS-CoV-2 by RT-PCR (in-house-laboratorydeveloped test detecting the N and ORF1ab genes by primers, with LightCycler 2.0 instrument from Roche, RotKreuz, Switzerland a ) 6 . Hence, we believe that our patient experienced co-infection with both endemic HCoV-HKU1 and pandemic SARS-CoV-2. Our case illustrates the importance of maintaining a high degree of suspicion and to note that positivity for a known virus on any respiratory multiplex assay does not exclude the possibility of co-infection with SARS-CoV-2 in a patient with a compatible clinical presentation and epidemiological history. ./cache/cord-308831-u5bj1sod.txt ./txt/cord-308831-u5bj1sod.txt