id author title date pages extension mime words sentences flesch summary cache txt cord-307842-7q2jd0mf Fox, Alisa Robust and specific secretory IgA against SARS-CoV-2 detected in human milk 2020-10-26 .txt text/plain 467 40 58 The SARS-CoV-2 immune response in human milk has not yet been examined, though protecting infants and young children from COVID-19 is critical for limiting community transmission, and preventing serious illness and death. Milk samples were initially evaluated for IgA binding reactivity by human IgA-specific ELISA to the 88 full trimeric SARS-CoV-2 Spike (Fig. 1) . It was evident that all samples obtained from COVID-19-89 recovered donors (100%), in undiluted form, exhibited binding activity significantly above that of the 90 pre-pandemic control milk samples, which did exhibit some low-level non-specific or cross-reactive 91 activity (Fig. 1a) . It was found 92 that all COVID-19-recovered samples exhibited endpoint titers significantly higher than control samples evident that most of the samples contained SARS-CoV-2-reactive IgA without necessarily containing 146 measurable IgG and/or IgM, which particularly in the case of IgG, would likely be derived in large part 147 from the serum. ./cache/cord-307842-7q2jd0mf.txt ./txt/cord-307842-7q2jd0mf.txt