id author title date pages extension mime words sentences flesch summary cache txt cord-307596-0bbxyyea Parhar, Harman S. Topical preparations to reduce SARS‐CoV‐2 aerosolization in head and neck mucosal surgery 2020-04-25 .txt text/plain 2377 129 42 AIM: The COVID‐19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has put health care workers at risk when exposed to aerosolized viral particles during upper airway mucosal surgery. 12, 13 There has been very little published, however, regarding whether there exist any topical agents that could be utilized preoperatively to potentially lower the viral load in the upper aerodigestive tract thereby mitigating any risk of viral aerosolization in persons undergoing head and neck mucosal surgery. 14 While studies on virucidal activity of PVP-I have not yet been performed specifically on SARS-CoV-2, there have been numerous in vitro studies demonstrating its effectiveness against multiple viruses including related coronaviruses. Though no topical therapies have been studied to specifically reduce the viral load and potential aerosolization of SARS-CoV-2 during upper airway mucosal surgery, PVP-I solutions have demonstrated effective virucidal activity against related coronaviruses in numerous studies. ./cache/cord-307596-0bbxyyea.txt ./txt/cord-307596-0bbxyyea.txt