id author title date pages extension mime words sentences flesch summary cache txt cord-305798-7b8rua4z Rivas-GarcĂ­a, S Rhabdomyolysis as the main manifestation of coronavirus disease 2019 2020-06-25 .txt text/plain 1133 76 53 Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first reported in Wuhan, China in the late December 2019. Recent patient case series published in the setting of COVID-19 infection in China have described myalgia and elevated CK as frequent findings. High levels of CK-MB (muscle and brain isoform) were found in 4.5% of a 201 patient case series in Wuhan, [3] showing a significant association with acute respiratory syndrome distress development. Muscle weakness and elevated serum CK levels were also commonly found in coronavirus case series reported in the 2003 outbreak of SARS and the 2012 outbreak of Middle East respiratory syndrome (MERS) [4] . Even if myalgia and CK elevation are relatively frequent, rhabdomyolysis symptoms have been rarely reported in SARS-CoV-2 outbreaks. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China ./cache/cord-305798-7b8rua4z.txt ./txt/cord-305798-7b8rua4z.txt