id author title date pages extension mime words sentences flesch summary cache txt cord-305610-v1hn934x Kerslake, Rachel Co-expression of peripheral olfactory receptors with SARS-CoV-2 infection mediators: Potential implications beyond loss of smell as a COVID-19 symptom 2020-06-17 .txt text/plain 3002 141 41 Using Gene Expression Profiling Interactive Analysis, The Cancer Genome Atlas, Genotype-Tissue Expression, cBioPortal and Shiny Methylation Analysis Resource Tool, we highlight the expression of peripheral ORs in both healthy and malignant tissues, and describe their co-expression with key mediators of SARS-CoV-2 infection, such as ACE2 and TMPRSS2, as well as cathepsin L (CTSL; another cellular protease mediating SARS-CoV-2 infection of host cells). The present study aimed to identify, both in normal and cancer tissues, the co-expression profile of a number of ORs which are known to be expressed in peripheral tissues in relationship to key mediators of the SARS-coV-2 infection, namely AcE2, TMPRSS2 and cTSL. In conclusion, the present study offers new data regarding the expression of ORs in peripheral tissues and their co-expression pattern with key mediators of SARS-coV-2 cell entry and infection (i.e., AcE2, TMPRSS2, and cTSL). ./cache/cord-305610-v1hn934x.txt ./txt/cord-305610-v1hn934x.txt