id author title date pages extension mime words sentences flesch summary cache txt cord-304295-3mpymd8a Khan, Muhammad Muzamil Emergence of novel coronavirus and progress toward treatment and vaccine 2020-06-04 .txt text/plain 2935 210 48 10 Favipiravir was effectively used against influenza and has the potential to inhibit viral RNA synthesis and a new study also supports its activity against SARS-CoV-2. 15 In another recent study, Gao et al found that chloroquine phosphate reduced the symptoms of pneumonia in SARS-CoV-2 patients and shortening the duration of disease. 67 Different technologies are being utilized to F I G U R E 1 Mechanism of action of HCQ and CQ by blocking binding of virus with ACE-2 receptors and increasing endosomal pH and preventing fusion with the cell develop potential vaccine for SARS-CoV-2 including DNA and mRNAbased nanoparticles. Clinical study for safety and efficacy of favipiravir in the treatment of novel coronavirus pneumonia (COVID-19) In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ./cache/cord-304295-3mpymd8a.txt ./txt/cord-304295-3mpymd8a.txt