id author title date pages extension mime words sentences flesch summary cache txt cord-302616-1uwrcvjx Steenblock, Charlotte Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis 2020-05-07 .txt text/plain 3872 201 41 title: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis Furthermore, it has to be considered that certain therapies impacting expression of ACE2 might also influence the RAAS and the neuroendocrine stress axis, which may lead to long-term consequences, as prolonged exposure to stressors increases the risk to develop major depressive, anxiety and post-traumatic stress disorders [42] . In addition to contributing to the progression of the immune response against viral infection, cytokines activate the HPA axis, resulting in the release of adrenal glucocorticoids [43] . In relation to coronavirus infections, it was shown that pulmonary stem/progenitor cells that express ACE2 are targeted by SARS-CoV in primary cultures [73] . Increasing brain angiotensin converting enzyme 2 activity Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis decreases anxiety-like behavior in male mice by activating central Mas receptors ./cache/cord-302616-1uwrcvjx.txt ./txt/cord-302616-1uwrcvjx.txt