id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-302163-0jav84zw	Anastassopoulou, Cleo	Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severity	2020-10-22		.txt	text/plain	4823	212	41	We searched PubMed/MEDLINE for all Englishlanguage original articles or reviews reporting on potential associations between human genetic factors and susceptibility to SARS-CoV-2 infection or COVID-19 severity, up to August 12, 2020 (with updating as of September 11, 2020, during the revision of the manuscript). The search was performed using all combinations of terms related to the novel coronavirus and the disease (e.g., "SARS-CoV-2," "2019-nCoV," and "COVID-19") on the one hand, and terms concerning susceptibility to infection or disease severity (e.g., "polymorphisms," "allelic variation," "genetic predisposition," "genotype," "clinical outcome") as well as the names of individual genes in which relevant polymorphisms were found (e.g., "TLR7," "ACE2"), on the other. A recently published comparative genetic analysis of approximately 81,000 human genomes across different populations suggested possible associations of coding region variants of ACE2 and TMPRSS2 with COVID-19 susceptibility, severity, and clinical outcomes [49] .	./cache/cord-302163-0jav84zw.txt	./txt/cord-302163-0jav84zw.txt