id author title date pages extension mime words sentences flesch summary cache txt cord-302075-ctd9sutv Tetro, Jason A. Is COVID-19 receiving ADE from other coronaviruses? 2020-02-22 .txt text/plain 1267 70 44 One of the most perplexing questions regarding the current COVID-19 coronavirus epidemic is the discrepancy between the severity of cases observed in the Hubei province of China and those occurring elsewhere in the world. ADE also requires prior exposure to similar antigenic epitopes, presumably circulating in local viruses, making it a possible explanation for the observed geographic limitation of severe cases and deaths. Notably, these observations in COVID-19 patients are similar to those who suffered from severe acute respiratory syndrome (SARS) during the 2003 epidemic [4] . Based on this information and the similarity of symptoms to SARS, COVID-19 appears to constitute a major threat to human health justifying the World Health Organization's declaration of a Public Health Emergency of International Concern. Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis Anti-severe acute respiratory syndrome coronavirus spike antibodies trigger infection of human immune cells via a pH-and cysteine protease-independent FcgR pathway ./cache/cord-302075-ctd9sutv.txt ./txt/cord-302075-ctd9sutv.txt