id author title date pages extension mime words sentences flesch summary cache txt cord-301876-d2j9wpqk Kalita, Parismita Design of a peptide-based subunit vaccine against novel coronavirus SARS-CoV-2 2020-05-04 .txt text/plain 3449 212 49 Few groups have designed subunit vaccines against SARS-CoV-2; however, their workflow involved either use of single protein for vaccine design [24, 25] or used only CTL epitopes without considering the importance of B-cell or HTL epitopes [26] . B-cell epitopes for the screened SARS-CoV-2 proteins were predicted using the ABCPred server (http://crdd.osdd.net/raghava/abcpred/). A total of 6 HTLs, 18 CTLs, and 9 B-cell epitopes derived from the three proteins were used to design the subunit vaccine (566 amino acid residues) against SARS-CoV-2 (Supplementary Figure 1) . Based on extensive bioinformatics analysis, we used three proteins to design a multi-epitope subunit vaccine against novel coronavirus SARS-CoV-2. Computational studies suggest that our multi-epitope based subunit vaccine has a probability of showing good protective efficacy and safety against SARS-CoV-2 infection in humans. Development of epitope-based peptide vaccine against novel coronavirus 2019 (SARS-COV-2): Immunoinformatics approach ./cache/cord-301876-d2j9wpqk.txt ./txt/cord-301876-d2j9wpqk.txt