id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-301638-2f8r37ns	Bonney, Glenn Kunnath	SARS-COV-2 associated acute pancreatitis: Cause, consequence or epiphenomenon?	2020-05-29		.txt	text/plain	709	55	54	title: SARS-COV-2 associated acute pancreatitis: Cause, consequence or epiphenomenon? The rapid spread of a novel coronavirus disease (COVID-19) caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2) has triggered a global pandemic. [2] The severity of AP observed varies from mild [1, 2] to severe,[43 but unfortunately accepted diagnostic criteria [4] was not used in these studies, raising the possibility that the elevated pancreatic enzymes may be due to other causes including increased gut permeability with SARS-CoV-2 infection. A study from 2010 using immunostaining found ACE2 to be highly expressed in islet cells and postulated that binding of SARS-CoV caused islet cell injury and hyperglycaemia in infected patients. [9] It is not known whether SARS-CoV-2 causes AP, whether the AP is a consequence of severe systemic inflammation and microvascular thrombosis from COVID-19 infection, or whether it is just an epiphenomenon. ACE2 Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2 Infection Coronavirus Disease-19 (COVID-19) associated with severe acute pancreatitis: Case report on three family members	./cache/cord-301638-2f8r37ns.txt	./txt/cord-301638-2f8r37ns.txt