id author title date pages extension mime words sentences flesch summary cache txt cord-297800-hnx213kp Bi, Qifang Epidemiology and Transmission of COVID-19 in Shenzhen China: Analysis of 391 cases and 1,286 of their close contacts 2020-03-04 .txt text/plain 5363 279 54 We compare cases identified through symptomatic surveillance and contact tracing, and estimate the time from symptom onset to confirmation, isolation, and hospitalization. We characterize differences in demographics and severity between cases identified through symptom-based surveillance and the monitoring of close case contacts, and estimate the time to key events, such as confirmation, isolation, and recovery. Using data from contact tracing, we characterize SARS-CoV-2 transmission by estimating key values, such as the household secondary attack rate, serial interval and observed reproductive number. Based on 48 pairs of cases with a clear infector-infectee relationship and time of symptom onset, we estimate that the serial interval is gamma distributed with mean 6.3 days (95% CI 5.2,7.6) and a standard deviation of 4.2 days (95% CI, 3.1,5.3) ( Figure 2B , Table S2 ). This analysis of early SARS-CoV-2 cases and their close contacts in Shenzhen China, provides insights into the natural history, transmission and control of this disease. ./cache/cord-297800-hnx213kp.txt ./txt/cord-297800-hnx213kp.txt