id author title date pages extension mime words sentences flesch summary cache txt cord-297202-oup8ptya Beer, Martin SARS‐CoV‐2 vaccination—A plea for fast and coordinated action 2020-07-01 .txt text/plain 449 30 56 If we assume that the level of herd immunity to halt the spread follows the 1 − 1/R 0 rule (Anderson, Heesterbeek, Klinkenberg, & Hollingsworth, 2020) and given conservative estimates for the basic reproduction number R 0 = 3 (Sanche et al., 2020) at least two-thirds of the world's population must mount an effective immune response against the virus to prevent recurrent outbreaks. Yes, an R t < 0.2 would halt the spread of SARS-CoV-2 in a given population at time t, but any re-introduction of the virus could catapult us back to where we were. Unless serological surveys suggest a much higher-than-expected silent exposure of the human population to SARS-CoV-2, there is no reasonable scenario to reach the required level of herd immunity under the 'reduce spread' paradigm that many countries have emulated. ./cache/cord-297202-oup8ptya.txt ./txt/cord-297202-oup8ptya.txt