id author title date pages extension mime words sentences flesch summary cache txt cord-296390-jv86w4j9 Shao, Chen Evolution of SARS-Co-2 RNA test results in a fatal Covid-19 patient: a case report 2020-05-11 .txt text/plain 1436 99 53 On day 9 after admission, chest CT scan showed diffuse ground-glass shadows in patient's bilateral lungs. How SARS-CoV-2-infected patients progress to critical disease is a key issue in clinical practice. He was confirmed as Covid-19 positive in February 2 nd by qPCR analysis for SARS-CoV-2RNA of samples collected by nasopharyngeal swabs. He progressed to septic shock, severe metabolic acidosis and respiratory acidosis occurred successively and then, the patient died on February 14 th . It is worthy to note that the patient received SARS-CoV-2 RNA tests by nasopharyngeal swabs six times ( Table 1 ). Since February 6 th , four times SARS-CoV-2 RNA testing by nasopharyngeal swabs were negative (Table 1) . Given the missed diagnosis of the potential bacterial infection, antibiotics treatment was started too later in this patient, which might have resulted in multi-organ failure due to a septic shock. Clinical manifestation and lung histological alteration showed that this patient suffered from SARS-CoV-2 viral pneumonia. ./cache/cord-296390-jv86w4j9.txt ./txt/cord-296390-jv86w4j9.txt