id author title date pages extension mime words sentences flesch summary cache txt cord-296319-fwn97wds Juno, J. A. Immunogenic profile of SARS-CoV-2 spike in individuals recovered from COVID-19 2020-05-21 .txt text/plain 5331 383 59 In 139 summary, antibody responses against both S and the RBD are consistently elicited in 140 SARS-CoV-2 infected individuals, the endpoints titres of which correlate significantly 141 with neutralising activity (r=0.55 and r=0.61 respectively) and ACE2 binding 142 inhibition (r=0.72 and r=0.72 respectively) in the plasma ( Figure S2) . 143 144 B cell responses to S antigens following SARS-CoV-2 infection 145 We next examined the frequency and specificity of class-switched B cells in 146 convalescent subjects using SARS-CoV-2 spike or RBD proteins as flow cytometric 147 probes. Clear antigen-specific populations of CD19 + IgD -B cells (gating in Figure S3 ) 148 binding spike, spike and RBD or RBD alone could be resolved in our cohort of 149 recovered from SARS-CoV-2 subjects, with minimal background staining in 150 uninfected controls (Figure 2A ; Figure S4 ). ./cache/cord-296319-fwn97wds.txt ./txt/cord-296319-fwn97wds.txt